Myosin XVI rabbit pAb

• Background :

  Function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development., similarity:Contains 1 IQ domain., similarity:Contains 2 myosin head-like domains., similarity:Contains 7 ANK repeats., subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells., subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.

• Description :

  Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. similarity: Contains 1 IQ domain. similarity: Contains 2 myosin head-like domains. similarity: Contains 7 ANK repeats. subcellular location: Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells. subunit: Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.

• UniProt :

  Q9Y6X6

• Swiss Prot :

  Q9Y6X6

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from Myosin XVI . at AA range: 1050-1130

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight :

  200kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  200kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells. .

• Other Product Names :

  MYO16; KIAA0865; MYO16B; NYAP3; Unconventional myosin-XVI; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3; Unconventional myosin-16

• Gene ID (Human) :

  23026